Kokan
Brand names,
Kokan
Analogs
Kokan
Brand Names Mixture
Kokan
Chemical_Formula
C17H21NO4
Kokan
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Kokan
fda sheet
Kokan
msds (material safety sheet)
Kokan
Synthesis Reference
No information avaliable
Kokan
Molecular Weight
303.353 g/mol
Kokan
Melting Point
195 oC
Kokan
H2O Solubility
1800 mg/L
Kokan
State
Solid
Kokan
LogP
2.393
Kokan
Dosage Forms
Liquid
Kokan
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Kokan
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Kokan
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Kokan
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Kokan
Patient Information
No information avaliable
Kokan
Organisms Affected
Humans and other mammals