Leaf

Leaf Brand names, Leaf Analogs

Leaf Brand Names Mixture

No information avaliable

Leaf Chemical_Formula

C₁₇H₂₁NO₄

Leaf RX_link

http://www.rxlist.com/cgi/generic/cocaine.htm

Leaf fda sheet

Leaf msds (material safety sheet)

Leaf MSDS

Leaf Synthesis Reference

No information avaliable

Leaf Molecular Weight

303.353 g/mol

Leaf Melting Point

195 ^oC

Leaf H₂O Solubility

1800 mg/L

Leaf State

Solid

Leaf LogP

2.393

Leaf Dosage Forms

Liquid

Leaf Indication

For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.

Leaf Pharmacology

Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.

Leaf Absorption

Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.

Leaf side effects and Toxicity

Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD₅₀ = 96 mg/kg

Leaf Patient Information