Cocaine Free Base
Brand names,
Cocaine Free Base
Analogs
Cocaine Free Base
Brand Names Mixture
Cocaine Free Base
Chemical_Formula
C17H21NO4
Cocaine Free Base
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Cocaine Free Base
fda sheet
Cocaine Free Base
msds (material safety sheet)
Cocaine Free Base
Synthesis Reference
No information avaliable
Cocaine Free Base
Molecular Weight
303.353 g/mol
Cocaine Free Base
Melting Point
195 oC
Cocaine Free Base
H2O Solubility
1800 mg/L
Cocaine Free Base
State
Solid
Cocaine Free Base
LogP
2.393
Cocaine Free Base
Dosage Forms
Liquid
Cocaine Free Base
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cocaine Free Base
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cocaine Free Base
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Cocaine Free Base
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Cocaine Free Base
Patient Information
No information avaliable
Cocaine Free Base
Organisms Affected
Humans and other mammals