Toke
Brand names,
Toke
Analogs
Toke
Brand Names Mixture
Toke
Chemical_Formula
C17H21NO4
Toke
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Toke
fda sheet
Toke
msds (material safety sheet)
Toke
Synthesis Reference
No information avaliable
Toke
Molecular Weight
303.353 g/mol
Toke
Melting Point
195 oC
Toke
H2O Solubility
1800 mg/L
Toke
State
Solid
Toke
LogP
2.393
Toke
Dosage Forms
Liquid
Toke
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Toke
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Toke
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Toke
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Toke
Patient Information
No information avaliable
Toke
Organisms Affected
Humans and other mammals