Isococain
Brand names,
Isococain
Analogs
Isococain
Brand Names Mixture
Isococain
Chemical_Formula
C17H21NO4
Isococain
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Isococain
fda sheet
Isococain
msds (material safety sheet)
Isococain
Synthesis Reference
No information avaliable
Isococain
Molecular Weight
303.353 g/mol
Isococain
Melting Point
195 oC
Isococain
H2O Solubility
1800 mg/L
Isococain
State
Solid
Isococain
LogP
2.393
Isococain
Dosage Forms
Liquid
Isococain
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Isococain
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Isococain
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Isococain
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Isococain
Patient Information
No information avaliable
Isococain
Organisms Affected
Humans and other mammals