Corine
Brand names,
Corine
Analogs
Corine
Brand Names Mixture
Corine
Chemical_Formula
C17H21NO4
Corine
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Corine
fda sheet
Corine
msds (material safety sheet)
Corine
Synthesis Reference
No information avaliable
Corine
Molecular Weight
303.353 g/mol
Corine
Melting Point
195 oC
Corine
H2O Solubility
1800 mg/L
Corine
State
Solid
Corine
LogP
2.393
Corine
Dosage Forms
Liquid
Corine
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Corine
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Corine
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Corine
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Corine
Patient Information
No information avaliable
Corine
Organisms Affected
Humans and other mammals