Cecil
Brand names,
Cecil
Analogs
Cecil
Brand Names Mixture
Cecil
Chemical_Formula
C17H21NO4
Cecil
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Cecil
fda sheet
Cecil
msds (material safety sheet)
Cecil
Synthesis Reference
No information avaliable
Cecil
Molecular Weight
303.353 g/mol
Cecil
Melting Point
195 oC
Cecil
H2O Solubility
1800 mg/L
Cecil
State
Solid
Cecil
LogP
2.393
Cecil
Dosage Forms
Liquid
Cecil
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cecil
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cecil
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Cecil
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Cecil
Patient Information
No information avaliable
Cecil
Organisms Affected
Humans and other mammals