Sleighride
Brand names,
Sleighride
Analogs
Sleighride
Brand Names Mixture
Sleighride
Chemical_Formula
C17H21NO4
Sleighride
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Sleighride
fda sheet
Sleighride
msds (material safety sheet)
Sleighride
Synthesis Reference
No information avaliable
Sleighride
Molecular Weight
303.353 g/mol
Sleighride
Melting Point
195 oC
Sleighride
H2O Solubility
1800 mg/L
Sleighride
State
Solid
Sleighride
LogP
2.393
Sleighride
Dosage Forms
Liquid
Sleighride
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Sleighride
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Sleighride
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Sleighride
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Sleighride
Patient Information
No information avaliable
Sleighride
Organisms Affected
Humans and other mammals