Isoflurophate
Brand names,
Isoflurophate
Analogs
Isoflurophate
Brand Names Mixture
Isoflurophate
Chemical_Formula
C6H14FO3P
Isoflurophate
RX_link
No information avaliable
Isoflurophate
fda sheet
Isoflurophate
msds (material safety sheet)
Isoflurophate
Synthesis Reference
No information avaliable
Isoflurophate
Molecular Weight
184.146 g/mol
Isoflurophate
Melting Point
-82 oC
Isoflurophate
H2O Solubility
1.54E+004 mg/L
Isoflurophate
State
Liquid
Isoflurophate
LogP
1.13
Isoflurophate
Dosage Forms
No information avaliable
Isoflurophate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Isoflurophate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Isoflurophate
Absorption
No information avaliable
Isoflurophate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Isoflurophate
Patient Information
No information avaliable
Isoflurophate
Organisms Affected
Humans and other mammals