Diflurophate
Brand names,
Diflurophate
Analogs
Diflurophate
Brand Names Mixture
Diflurophate
Chemical_Formula
C6H14FO3P
Diflurophate
RX_link
No information avaliable
Diflurophate
fda sheet
Diflurophate
msds (material safety sheet)
Diflurophate
Synthesis Reference
No information avaliable
Diflurophate
Molecular Weight
184.146 g/mol
Diflurophate
Melting Point
-82 oC
Diflurophate
H2O Solubility
1.54E+004 mg/L
Diflurophate
State
Liquid
Diflurophate
LogP
1.13
Diflurophate
Dosage Forms
No information avaliable
Diflurophate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diflurophate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diflurophate
Absorption
No information avaliable
Diflurophate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diflurophate
Patient Information
No information avaliable
Diflurophate
Organisms Affected
Humans and other mammals