Diisopropyl Fluorophosphonate
Brand names,
Diisopropyl Fluorophosphonate
Analogs
Diisopropyl Fluorophosphonate
Brand Names Mixture
Diisopropyl Fluorophosphonate
Chemical_Formula
C6H14FO3P
Diisopropyl Fluorophosphonate
RX_link
No information avaliable
Diisopropyl Fluorophosphonate
fda sheet
Diisopropyl Fluorophosphonate
msds (material safety sheet)
Diisopropyl Fluorophosphonate
Synthesis Reference
No information avaliable
Diisopropyl Fluorophosphonate
Molecular Weight
184.146 g/mol
Diisopropyl Fluorophosphonate
Melting Point
-82 oC
Diisopropyl Fluorophosphonate
H2O Solubility
1.54E+004 mg/L
Diisopropyl Fluorophosphonate
State
Liquid
Diisopropyl Fluorophosphonate
LogP
1.13
Diisopropyl Fluorophosphonate
Dosage Forms
No information avaliable
Diisopropyl Fluorophosphonate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropyl Fluorophosphonate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropyl Fluorophosphonate
Absorption
No information avaliable
Diisopropyl Fluorophosphonate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropyl Fluorophosphonate
Patient Information
No information avaliable
Diisopropyl Fluorophosphonate
Organisms Affected
Humans and other mammals