Isofluorphate
Brand names,
Isofluorphate
Analogs
Isofluorphate
Brand Names Mixture
Isofluorphate
Chemical_Formula
C6H14FO3P
Isofluorphate
RX_link
No information avaliable
Isofluorphate
fda sheet
Isofluorphate
msds (material safety sheet)
Isofluorphate
Synthesis Reference
No information avaliable
Isofluorphate
Molecular Weight
184.146 g/mol
Isofluorphate
Melting Point
-82 oC
Isofluorphate
H2O Solubility
1.54E+004 mg/L
Isofluorphate
State
Liquid
Isofluorphate
LogP
1.13
Isofluorphate
Dosage Forms
No information avaliable
Isofluorphate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Isofluorphate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Isofluorphate
Absorption
No information avaliable
Isofluorphate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Isofluorphate
Patient Information
No information avaliable
Isofluorphate
Organisms Affected
Humans and other mammals