Isopropyl Phosphorofluoridate
Brand names,
Isopropyl Phosphorofluoridate
Analogs
Isopropyl Phosphorofluoridate
Brand Names Mixture
Isopropyl Phosphorofluoridate
Chemical_Formula
C6H14FO3P
Isopropyl Phosphorofluoridate
RX_link
No information avaliable
Isopropyl Phosphorofluoridate
fda sheet
Isopropyl Phosphorofluoridate
msds (material safety sheet)
Isopropyl Phosphorofluoridate
Synthesis Reference
No information avaliable
Isopropyl Phosphorofluoridate
Molecular Weight
184.146 g/mol
Isopropyl Phosphorofluoridate
Melting Point
-82 oC
Isopropyl Phosphorofluoridate
H2O Solubility
1.54E+004 mg/L
Isopropyl Phosphorofluoridate
State
Liquid
Isopropyl Phosphorofluoridate
LogP
1.13
Isopropyl Phosphorofluoridate
Dosage Forms
No information avaliable
Isopropyl Phosphorofluoridate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Isopropyl Phosphorofluoridate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Isopropyl Phosphorofluoridate
Absorption
No information avaliable
Isopropyl Phosphorofluoridate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Isopropyl Phosphorofluoridate
Patient Information
No information avaliable
Isopropyl Phosphorofluoridate
Organisms Affected
Humans and other mammals