Diisopropylfluorfosfat
Brand names,
Diisopropylfluorfosfat
Analogs
Diisopropylfluorfosfat
Brand Names Mixture
Diisopropylfluorfosfat
Chemical_Formula
C6H14FO3P
Diisopropylfluorfosfat
RX_link
No information avaliable
Diisopropylfluorfosfat
fda sheet
Diisopropylfluorfosfat
msds (material safety sheet)
Diisopropylfluorfosfat
Synthesis Reference
No information avaliable
Diisopropylfluorfosfat
Molecular Weight
184.146 g/mol
Diisopropylfluorfosfat
Melting Point
-82 oC
Diisopropylfluorfosfat
H2O Solubility
1.54E+004 mg/L
Diisopropylfluorfosfat
State
Liquid
Diisopropylfluorfosfat
LogP
1.13
Diisopropylfluorfosfat
Dosage Forms
No information avaliable
Diisopropylfluorfosfat
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropylfluorfosfat
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropylfluorfosfat
Absorption
No information avaliable
Diisopropylfluorfosfat
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropylfluorfosfat
Patient Information
No information avaliable
Diisopropylfluorfosfat
Organisms Affected
Humans and other mammals