DFP
Brand names,
DFP
Analogs
DFP
Brand Names Mixture
DFP
Chemical_Formula
C6H14FO3P
DFP
RX_link
No information avaliable
DFP
fda sheet
DFP
msds (material safety sheet)
DFP
Synthesis Reference
No information avaliable
DFP
Molecular Weight
184.146 g/mol
DFP
Melting Point
-82 oC
DFP
H2O Solubility
1.54E+004 mg/L
DFP
State
Liquid
DFP
LogP
1.13
DFP
Dosage Forms
No information avaliable
DFP
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
DFP
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
DFP
Absorption
No information avaliable
DFP
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
DFP
Patient Information
No information avaliable
DFP
Organisms Affected
Humans and other mammals