Diisopropylfluorophosphoric Acid Ester
Brand names,
Diisopropylfluorophosphoric Acid Ester
Analogs
Diisopropylfluorophosphoric Acid Ester
Brand Names Mixture
Diisopropylfluorophosphoric Acid Ester
Chemical_Formula
C6H14FO3P
Diisopropylfluorophosphoric Acid Ester
RX_link
No information avaliable
Diisopropylfluorophosphoric Acid Ester
fda sheet
Diisopropylfluorophosphoric Acid Ester
msds (material safety sheet)
Diisopropylfluorophosphoric Acid Ester
Synthesis Reference
No information avaliable
Diisopropylfluorophosphoric Acid Ester
Molecular Weight
184.146 g/mol
Diisopropylfluorophosphoric Acid Ester
Melting Point
-82 oC
Diisopropylfluorophosphoric Acid Ester
H2O Solubility
1.54E+004 mg/L
Diisopropylfluorophosphoric Acid Ester
State
Liquid
Diisopropylfluorophosphoric Acid Ester
LogP
1.13
Diisopropylfluorophosphoric Acid Ester
Dosage Forms
No information avaliable
Diisopropylfluorophosphoric Acid Ester
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropylfluorophosphoric Acid Ester
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropylfluorophosphoric Acid Ester
Absorption
No information avaliable
Diisopropylfluorophosphoric Acid Ester
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropylfluorophosphoric Acid Ester
Patient Information
No information avaliable
Diisopropylfluorophosphoric Acid Ester
Organisms Affected
Humans and other mammals