Diisopropyl Fluoridophosphate
Brand names,
Diisopropyl Fluoridophosphate
Analogs
Diisopropyl Fluoridophosphate
Brand Names Mixture
Diisopropyl Fluoridophosphate
Chemical_Formula
C6H14FO3P
Diisopropyl Fluoridophosphate
RX_link
No information avaliable
Diisopropyl Fluoridophosphate
fda sheet
Diisopropyl Fluoridophosphate
msds (material safety sheet)
Diisopropyl Fluoridophosphate
Synthesis Reference
No information avaliable
Diisopropyl Fluoridophosphate
Molecular Weight
184.146 g/mol
Diisopropyl Fluoridophosphate
Melting Point
-82 oC
Diisopropyl Fluoridophosphate
H2O Solubility
1.54E+004 mg/L
Diisopropyl Fluoridophosphate
State
Liquid
Diisopropyl Fluoridophosphate
LogP
1.13
Diisopropyl Fluoridophosphate
Dosage Forms
No information avaliable
Diisopropyl Fluoridophosphate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropyl Fluoridophosphate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropyl Fluoridophosphate
Absorption
No information avaliable
Diisopropyl Fluoridophosphate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropyl Fluoridophosphate
Patient Information
No information avaliable
Diisopropyl Fluoridophosphate
Organisms Affected
Humans and other mammals