Isopropyl Fluophosphate
Brand names,
Isopropyl Fluophosphate
Analogs
Isopropyl Fluophosphate
Brand Names Mixture
Isopropyl Fluophosphate
Chemical_Formula
C6H14FO3P
Isopropyl Fluophosphate
RX_link
No information avaliable
Isopropyl Fluophosphate
fda sheet
Isopropyl Fluophosphate
msds (material safety sheet)
Isopropyl Fluophosphate
Synthesis Reference
No information avaliable
Isopropyl Fluophosphate
Molecular Weight
184.146 g/mol
Isopropyl Fluophosphate
Melting Point
-82 oC
Isopropyl Fluophosphate
H2O Solubility
1.54E+004 mg/L
Isopropyl Fluophosphate
State
Liquid
Isopropyl Fluophosphate
LogP
1.13
Isopropyl Fluophosphate
Dosage Forms
No information avaliable
Isopropyl Fluophosphate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Isopropyl Fluophosphate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Isopropyl Fluophosphate
Absorption
No information avaliable
Isopropyl Fluophosphate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Isopropyl Fluophosphate
Patient Information
No information avaliable
Isopropyl Fluophosphate
Organisms Affected
Humans and other mammals