Fluorodiisopropyl Phosphate
Brand names,
Fluorodiisopropyl Phosphate
Analogs
Fluorodiisopropyl Phosphate
Brand Names Mixture
Fluorodiisopropyl Phosphate
Chemical_Formula
C6H14FO3P
Fluorodiisopropyl Phosphate
RX_link
No information avaliable
Fluorodiisopropyl Phosphate
fda sheet
Fluorodiisopropyl Phosphate
msds (material safety sheet)
Fluorodiisopropyl Phosphate
Synthesis Reference
No information avaliable
Fluorodiisopropyl Phosphate
Molecular Weight
184.146 g/mol
Fluorodiisopropyl Phosphate
Melting Point
-82 oC
Fluorodiisopropyl Phosphate
H2O Solubility
1.54E+004 mg/L
Fluorodiisopropyl Phosphate
State
Liquid
Fluorodiisopropyl Phosphate
LogP
1.13
Fluorodiisopropyl Phosphate
Dosage Forms
No information avaliable
Fluorodiisopropyl Phosphate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Fluorodiisopropyl Phosphate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Fluorodiisopropyl Phosphate
Absorption
No information avaliable
Fluorodiisopropyl Phosphate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Fluorodiisopropyl Phosphate
Patient Information
No information avaliable
Fluorodiisopropyl Phosphate
Organisms Affected
Humans and other mammals