Diisopropyl Phosphofluoridate
Brand names,
Diisopropyl Phosphofluoridate
Analogs
Diisopropyl Phosphofluoridate
Brand Names Mixture
Diisopropyl Phosphofluoridate
Chemical_Formula
C6H14FO3P
Diisopropyl Phosphofluoridate
RX_link
No information avaliable
Diisopropyl Phosphofluoridate
fda sheet
Diisopropyl Phosphofluoridate
msds (material safety sheet)
Diisopropyl Phosphofluoridate
Synthesis Reference
No information avaliable
Diisopropyl Phosphofluoridate
Molecular Weight
184.146 g/mol
Diisopropyl Phosphofluoridate
Melting Point
-82 oC
Diisopropyl Phosphofluoridate
H2O Solubility
1.54E+004 mg/L
Diisopropyl Phosphofluoridate
State
Liquid
Diisopropyl Phosphofluoridate
LogP
1.13
Diisopropyl Phosphofluoridate
Dosage Forms
No information avaliable
Diisopropyl Phosphofluoridate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropyl Phosphofluoridate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropyl Phosphofluoridate
Absorption
No information avaliable
Diisopropyl Phosphofluoridate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropyl Phosphofluoridate
Patient Information
No information avaliable
Diisopropyl Phosphofluoridate
Organisms Affected
Humans and other mammals