Phospholine Iodide
Brand names,
Phospholine Iodide
Analogs
Phospholine Iodide
Brand Names Mixture
Phospholine Iodide
Chemical_Formula
C6H14FO3P
Phospholine Iodide
RX_link
No information avaliable
Phospholine Iodide
fda sheet
Phospholine Iodide
msds (material safety sheet)
Phospholine Iodide
Synthesis Reference
No information avaliable
Phospholine Iodide
Molecular Weight
184.146 g/mol
Phospholine Iodide
Melting Point
-82 oC
Phospholine Iodide
H2O Solubility
1.54E+004 mg/L
Phospholine Iodide
State
Liquid
Phospholine Iodide
LogP
1.13
Phospholine Iodide
Dosage Forms
No information avaliable
Phospholine Iodide
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Phospholine Iodide
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Phospholine Iodide
Absorption
No information avaliable
Phospholine Iodide
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Phospholine Iodide
Patient Information
No information avaliable
Phospholine Iodide
Organisms Affected
Humans and other mammals