O,O-Diisopropyl Fluorophosphate
Brand names,
O,O-Diisopropyl Fluorophosphate
Analogs
O,O-Diisopropyl Fluorophosphate
Brand Names Mixture
O,O-Diisopropyl Fluorophosphate
Chemical_Formula
C6H14FO3P
O,O-Diisopropyl Fluorophosphate
RX_link
No information avaliable
O,O-Diisopropyl Fluorophosphate
fda sheet
O,O-Diisopropyl Fluorophosphate
msds (material safety sheet)
O,O-Diisopropyl Fluorophosphate
Synthesis Reference
No information avaliable
O,O-Diisopropyl Fluorophosphate
Molecular Weight
184.146 g/mol
O,O-Diisopropyl Fluorophosphate
Melting Point
-82 oC
O,O-Diisopropyl Fluorophosphate
H2O Solubility
1.54E+004 mg/L
O,O-Diisopropyl Fluorophosphate
State
Liquid
O,O-Diisopropyl Fluorophosphate
LogP
1.13
O,O-Diisopropyl Fluorophosphate
Dosage Forms
No information avaliable
O,O-Diisopropyl Fluorophosphate
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
O,O-Diisopropyl Fluorophosphate
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
O,O-Diisopropyl Fluorophosphate
Absorption
No information avaliable
O,O-Diisopropyl Fluorophosphate
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
O,O-Diisopropyl Fluorophosphate
Patient Information
No information avaliable
O,O-Diisopropyl Fluorophosphate
Organisms Affected
Humans and other mammals