Diisopropylfluorphosphorsaeureester
Brand names,
Diisopropylfluorphosphorsaeureester
Analogs
Diisopropylfluorphosphorsaeureester
Brand Names Mixture
Diisopropylfluorphosphorsaeureester
Chemical_Formula
C6H14FO3P
Diisopropylfluorphosphorsaeureester
RX_link
No information avaliable
Diisopropylfluorphosphorsaeureester
fda sheet
Diisopropylfluorphosphorsaeureester
msds (material safety sheet)
Diisopropylfluorphosphorsaeureester
Synthesis Reference
No information avaliable
Diisopropylfluorphosphorsaeureester
Molecular Weight
184.146 g/mol
Diisopropylfluorphosphorsaeureester
Melting Point
-82 oC
Diisopropylfluorphosphorsaeureester
H2O Solubility
1.54E+004 mg/L
Diisopropylfluorphosphorsaeureester
State
Liquid
Diisopropylfluorphosphorsaeureester
LogP
1.13
Diisopropylfluorphosphorsaeureester
Dosage Forms
No information avaliable
Diisopropylfluorphosphorsaeureester
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropylfluorphosphorsaeureester
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropylfluorphosphorsaeureester
Absorption
No information avaliable
Diisopropylfluorphosphorsaeureester
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropylfluorphosphorsaeureester
Patient Information
No information avaliable
Diisopropylfluorphosphorsaeureester
Organisms Affected
Humans and other mammals