Diisopropoxyphosphoryl Fluoride
Brand names,
Diisopropoxyphosphoryl Fluoride
Analogs
Diisopropoxyphosphoryl Fluoride
Brand Names Mixture
Diisopropoxyphosphoryl Fluoride
Chemical_Formula
C6H14FO3P
Diisopropoxyphosphoryl Fluoride
RX_link
No information avaliable
Diisopropoxyphosphoryl Fluoride
fda sheet
Diisopropoxyphosphoryl Fluoride
msds (material safety sheet)
Diisopropoxyphosphoryl Fluoride
Synthesis Reference
No information avaliable
Diisopropoxyphosphoryl Fluoride
Molecular Weight
184.146 g/mol
Diisopropoxyphosphoryl Fluoride
Melting Point
-82 oC
Diisopropoxyphosphoryl Fluoride
H2O Solubility
1.54E+004 mg/L
Diisopropoxyphosphoryl Fluoride
State
Liquid
Diisopropoxyphosphoryl Fluoride
LogP
1.13
Diisopropoxyphosphoryl Fluoride
Dosage Forms
No information avaliable
Diisopropoxyphosphoryl Fluoride
Indication
For use in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia.
Diisopropoxyphosphoryl Fluoride
Pharmacology
Isoflurophate is used as ocular drops in the treatment of chronic glaucoma. Isoflurophate is an organophosphorus compound that acts as an irreversible cholinesterase inhibitor. As such, it displays parasympathomimetic effects. Isoflurophate is used in the eye to treat certain types of glaucoma and other eye conditions, such as accommodative esotropia. They may also be used in the diagnosis of certain eye conditions, such as accommodative esotropia. Isoflurophate damages the acetylcholinesterase enzyme and is therefore irreversible, however, pralidoxime can displace organophosphates such as isoflurophate from acetylcholinesterase, but only if administered before isoflurophate damages (alkylates) the enzyme.
Diisopropoxyphosphoryl Fluoride
Absorption
No information avaliable
Diisopropoxyphosphoryl Fluoride
side effects and Toxicity
Signs of overdose include increased sweating, loss of bladder control, muscle weakness, nausea, vomiting, diarrhea, or stomach cramps or pain, shortness of breath, tightness in chest, or wheezing, slow or irregular heartbeat, unusual tiredness or weakness, watering of mouth.
Diisopropoxyphosphoryl Fluoride
Patient Information
No information avaliable
Diisopropoxyphosphoryl Fluoride
Organisms Affected
Humans and other mammals