Cocaine, L-
Brand names,
Cocaine, L-
Analogs
Cocaine, L-
Brand Names Mixture
Cocaine, L-
Chemical_Formula
C17H21NO4
Cocaine, L-
RX_link
http://www.rxlist.com/cgi/generic/cocaine.htm
Cocaine, L-
fda sheet
Cocaine, L-
msds (material safety sheet)
Cocaine, L-
Synthesis Reference
No information avaliable
Cocaine, L-
Molecular Weight
303.353 g/mol
Cocaine, L-
Melting Point
195 oC
Cocaine, L-
H2O Solubility
1800 mg/L
Cocaine, L-
State
Solid
Cocaine, L-
LogP
2.393
Cocaine, L-
Dosage Forms
Liquid
Cocaine, L-
Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cocaine, L-
Pharmacology
Cocaine is a local anesthetic indicated for the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
Cocaine, L-
Absorption
Cocaine is absorbed from all sites of application, including mucous membranes and gastrointestinal mucosa. By oral or intra-nasal route, 60 to 80% of cocaine is absorbed.
Cocaine, L-
side effects and Toxicity
Intense agitation, convulsions, hypertension, rhythm disturbance, coronary insufficiency, hyperthermia, rhabdomyolysis, and renal impairment. Oral mouse LD50 = 96 mg/kg
Cocaine, L-
Patient Information
No information avaliable
Cocaine, L-
Organisms Affected
Humans and other mammals