Categoria
Calan
Marchi,
Calan
Analoghi
Calan
Marchi miscela
Tarka (trandolapril + verapamil hydrochloride)
Calan
Formula chimica
C27H38N2O4
Calan
RX link
http://www.rxlist.com/cgi/generic/verapsr.htm
Calan
FDA foglio
Calan
DMS (foglio di materiale di sicurezza)
Calan
Sintesi di riferimento
Dengel, US Pat. 3,261,859 (1966)
Calan
Peso molecolare
454.602 g/mol
Calan
Temperatura di fusione
< 25 oC
Calan
H2O Solubilita
4,47 mg / L
Calan
Stato
Liquid
Calan
LogP
5.931
Calan
Forme di dosaggio
Capsule (rilascio prolungato); liquidi; soluzione; Tablet; Tablet (a rilascio prolungato)
Calan
Indicazione
Per il trattamento di ipertensione e angina.
Calan
Farmacologia
Verapamil, un agente antiaritmico di classe IV, viene utilizzato come inibitore dei canali del blocco (CCB), agente per il trattamento dell'angina, ipertensione, e per tachiaritmie sopraventricolari.
Calan
Assorbimento
90%
Calan
Tossicita
LD50 = 8 mg / kg (iv nei topi)
Calan
Informazioni paziente
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Calan
Atto interessato organismi
Gli esseri umani e altri mammiferi