Categorie
Verelan PM
Les marques,
Verelan PM
Analogs
Verelan PM
Les marques melange
Tarka (trandolapril + verapamil hydrochloride)
Verelan PM
Formule chimique
C27H38N2O4
Verelan PM
RX lien
http://www.rxlist.com/cgi/generic/verapsr.htm
Verelan PM
FDA fiche
Verelan PM
msds (fiche de securite des materiaux)
Verelan PM
Synthese de reference
Dengel, le brevet américain. 3,261,859 (1966)
Verelan PM
Poids moleculaire
454.602 g/mol
Verelan PM
Point de fusion
< 25 oC
Verelan PM
H2O Solubilite
4,47 mg / L
Verelan PM
Etat
Liquid
Verelan PM
LogP
5.931
Verelan PM
Formes pharmaceutiques
Capsule (libération prolongée); liquide; Solution; Tablet; Tablet (libération prolongée)
Verelan PM
Indication
Pour le traitement de l'hypertension et l'angine.
Verelan PM
Pharmacologie
Vérapamil, un anti-arythmique de classe IV agent, est utilisé comme un blocage des canaux calciques (BCC) agent pour le traitement de l'angine, l'hypertension, et pour tachyarythmies supraventriculaires.
Verelan PM
Absorption
90%
Verelan PM
Toxicite
DL50 = 8 mg / kg (iv chez la souris)
Verelan PM
Information pour les patients
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Verelan PM
Organismes affectes
Les humains et autres mammifères