Categorie
Verapamil HCl
Les marques,
Verapamil HCl
Analogs
Verapamil HCl
Les marques melange
Tarka (trandolapril + verapamil hydrochloride)
Verapamil HCl
Formule chimique
C27H38N2O4
Verapamil HCl
RX lien
http://www.rxlist.com/cgi/generic/verapsr.htm
Verapamil HCl
FDA fiche
Verapamil HCl
msds (fiche de securite des materiaux)
Verapamil HCl
Synthese de reference
Dengel, le brevet américain. 3,261,859 (1966)
Verapamil HCl
Poids moleculaire
454.602 g/mol
Verapamil HCl
Point de fusion
< 25 oC
Verapamil HCl
H2O Solubilite
4,47 mg / L
Verapamil HCl
Etat
Liquid
Verapamil HCl
LogP
5.931
Verapamil HCl
Formes pharmaceutiques
Capsule (libération prolongée); liquide; Solution; Tablet; Tablet (libération prolongée)
Verapamil HCl
Indication
Pour le traitement de l'hypertension et l'angine.
Verapamil HCl
Pharmacologie
Vérapamil, un anti-arythmique de classe IV agent, est utilisé comme un blocage des canaux calciques (BCC) agent pour le traitement de l'angine, l'hypertension, et pour tachyarythmies supraventriculaires.
Verapamil HCl
Absorption
90%
Verapamil HCl
Toxicite
DL50 = 8 mg / kg (iv chez la souris)
Verapamil HCl
Information pour les patients
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Verapamil HCl
Organismes affectes
Les humains et autres mammifères