Categorie
Cardibeltin
Les marques,
Cardibeltin
Analogs
Cardibeltin
Les marques melange
Tarka (trandolapril + verapamil hydrochloride)
Cardibeltin
Formule chimique
C27H38N2O4
Cardibeltin
RX lien
http://www.rxlist.com/cgi/generic/verapsr.htm
Cardibeltin
FDA fiche
Cardibeltin
msds (fiche de securite des materiaux)
Cardibeltin
Synthese de reference
Dengel, le brevet américain. 3,261,859 (1966)
Cardibeltin
Poids moleculaire
454.602 g/mol
Cardibeltin
Point de fusion
< 25 oC
Cardibeltin
H2O Solubilite
4,47 mg / L
Cardibeltin
Etat
Liquid
Cardibeltin
LogP
5.931
Cardibeltin
Formes pharmaceutiques
Capsule (libération prolongée); liquide; Solution; Tablet; Tablet (libération prolongée)
Cardibeltin
Indication
Pour le traitement de l'hypertension et l'angine.
Cardibeltin
Pharmacologie
Vérapamil, un anti-arythmique de classe IV agent, est utilisé comme un blocage des canaux calciques (BCC) agent pour le traitement de l'angine, l'hypertension, et pour tachyarythmies supraventriculaires.
Cardibeltin
Absorption
90%
Cardibeltin
Toxicite
DL50 = 8 mg / kg (iv chez la souris)
Cardibeltin
Information pour les patients
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Cardibeltin
Organismes affectes
Les humains et autres mammifères