Categorie
Calan SR
Les marques,
Calan SR
Analogs
Calan SR
Les marques melange
Tarka (trandolapril + verapamil hydrochloride)
Calan SR
Formule chimique
C27H38N2O4
Calan SR
RX lien
http://www.rxlist.com/cgi/generic/verapsr.htm
Calan SR
FDA fiche
Calan SR
msds (fiche de securite des materiaux)
Calan SR
Synthese de reference
Dengel, le brevet américain. 3,261,859 (1966)
Calan SR
Poids moleculaire
454.602 g/mol
Calan SR
Point de fusion
< 25 oC
Calan SR
H2O Solubilite
4,47 mg / L
Calan SR
Etat
Liquid
Calan SR
LogP
5.931
Calan SR
Formes pharmaceutiques
Capsule (libération prolongée); liquide; Solution; Tablet; Tablet (libération prolongée)
Calan SR
Indication
Pour le traitement de l'hypertension et l'angine.
Calan SR
Pharmacologie
Vérapamil, un anti-arythmique de classe IV agent, est utilisé comme un blocage des canaux calciques (BCC) agent pour le traitement de l'angine, l'hypertension, et pour tachyarythmies supraventriculaires.
Calan SR
Absorption
90%
Calan SR
Toxicite
DL50 = 8 mg / kg (iv chez la souris)
Calan SR
Information pour les patients
Verapamil HCl is known as a calcium channel blocker. It is taken to treat high blood pressure, to relieve some
chest pains in patients with angina, or to treat some problems with heart rhythms. Verapamil has several drug
interactions, make sure your physician and pharmacist known all the medicines you are taking so they may properly
advise you. Verapamil HCl is excreted in breast milk. It may be necessary to change therapy or provide an alternate
to breast milk. The most common side effect is constipation. This may be relieved with dietary modification (more
fiber) or laxatives. Sustained release tablets should be taken with food. They should not be broken or crushed. Doses
may need some adjustment, make sure to have your condition monitored regularly.
Calan SR
Organismes affectes
Les humains et autres mammifères