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Trittico Brand names, Trittico Analogs

Trittico Brand Names Mixture

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Trittico Chemical_Formula


Trittico RX_link

Trittico fda sheet

Trittico FDA

Trittico msds (material safety sheet)

Trittico Synthesis Reference

Palazzo, Silvestrini, U.S. Pat 3,381,009 (1968)

Trittico Molecular Weight

371.864 g/mol

Trittico Melting Point

86-87 oC

Trittico H2O Solubility

Sparigly soluble

Trittico State


Trittico LogP


Trittico Dosage Forms


Trittico Indication

For the treatment of depression.

Trittico Pharmacology

Trazodone is an antidepressant and hypnotic chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. The mechanism of trazodone's antidepressant action in man is not fully understood. In animals, trazodone selectively inhibits serotonin uptake by brain synaptosomes and potentiates the behavioral changes induced by the serotonin precursor, 5-hydroxytryptophan. Cardiac conduction effects of trazodone in the anesthetized dog are qualitatively dissimilar and quantitatively less pronounced than those seen with tricyclic antidepressants. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. In man, trazodone is well absorbed after oral administration without selective localization in any tissue. Since the clearance of trazodone from the body is sufficiently variable, in some patients trazodone may accumulate in the plasma.

Trittico Absorption

Well absorbed following oral administration.

Trittico side effects and Toxicity

LD50=96mg/kg (i.v. in mice)

Trittico Patient Information

Trittico Organisms Affected

Humans and other mammals