Molipaxin
Molipaxin Brand names, Molipaxin Analogs
Molipaxin Brand Names Mixture
- No information avaliable
Molipaxin Chemical_Formula
C19H22ClN5O
Molipaxin RX_link
http://www.rxlist.com/cgi/generic/traz.htm
Molipaxin fda sheet
Molipaxin msds (material safety sheet)
Molipaxin Synthesis Reference
Palazzo, Silvestrini, U.S. Pat 3,381,009 (1968)
Molipaxin Molecular Weight
371.864 g/mol
Molipaxin Melting Point
86-87 oC
Molipaxin H2O Solubility
Sparigly soluble
Molipaxin State
Solid
Molipaxin LogP
2.553
Molipaxin Dosage Forms
Tablet
Molipaxin Indication
For the treatment of depression.
Molipaxin Pharmacology
Trazodone is an antidepressant and hypnotic chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. The mechanism of trazodone's antidepressant action in man is not fully understood. In animals, trazodone selectively inhibits serotonin uptake by brain synaptosomes and potentiates the behavioral changes induced by the serotonin precursor, 5-hydroxytryptophan. Cardiac conduction effects of trazodone in the anesthetized dog are qualitatively dissimilar and quantitatively less pronounced than those seen with tricyclic antidepressants. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. In man, trazodone is well absorbed after oral administration without selective localization in any tissue. Since the clearance of trazodone from the body is sufficiently variable, in some patients trazodone may accumulate in the plasma.
Molipaxin Absorption
Well absorbed following oral administration.
Molipaxin side effects and Toxicity
LD50=96mg/kg (i.v. in mice)
Molipaxin Patient Information
Molipaxin Organisms Affected
Humans and other mammals
