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Bimaran Brand names, Bimaran Analogs

Bimaran Brand Names Mixture

  • No information avaliable

Bimaran Chemical_Formula

C19H22ClN5O

Bimaran RX_link

http://www.rxlist.com/cgi/generic/traz.htm

Bimaran fda sheet

Bimaran FDA

Bimaran msds (material safety sheet)

Bimaran Synthesis Reference

Palazzo, Silvestrini, U.S. Pat 3,381,009 (1968)

Bimaran Molecular Weight

371.864 g/mol

Bimaran Melting Point

86-87 oC

Bimaran H2O Solubility

Sparigly soluble

Bimaran State

Solid

Bimaran LogP

2.553

Bimaran Dosage Forms

Tablet

Bimaran Indication

For the treatment of depression.

Bimaran Pharmacology

Trazodone is an antidepressant and hypnotic chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. The mechanism of trazodone's antidepressant action in man is not fully understood. In animals, trazodone selectively inhibits serotonin uptake by brain synaptosomes and potentiates the behavioral changes induced by the serotonin precursor, 5-hydroxytryptophan. Cardiac conduction effects of trazodone in the anesthetized dog are qualitatively dissimilar and quantitatively less pronounced than those seen with tricyclic antidepressants. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. In man, trazodone is well absorbed after oral administration without selective localization in any tissue. Since the clearance of trazodone from the body is sufficiently variable, in some patients trazodone may accumulate in the plasma.

Bimaran Absorption

Well absorbed following oral administration.

Bimaran side effects and Toxicity

LD50=96mg/kg (i.v. in mice)

Bimaran Patient Information

Bimaran Organisms Affected

Humans and other mammals