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Trazalon Brand names, Trazalon Analogs

Trazalon Brand Names Mixture

  • No information avaliable

Trazalon Chemical_Formula


Trazalon RX_link

Trazalon fda sheet

Trazalon FDA

Trazalon msds (material safety sheet)

Trazalon Synthesis Reference

Palazzo, Silvestrini, U.S. Pat 3,381,009 (1968)

Trazalon Molecular Weight

371.864 g/mol

Trazalon Melting Point

86-87 oC

Trazalon H2O Solubility

Sparigly soluble

Trazalon State


Trazalon LogP


Trazalon Dosage Forms


Trazalon Indication

For the treatment of depression.

Trazalon Pharmacology

Trazodone is an antidepressant and hypnotic chemically unrelated to tricyclic, tetracyclic, or other known antidepressant agents. The mechanism of trazodone's antidepressant action in man is not fully understood. In animals, trazodone selectively inhibits serotonin uptake by brain synaptosomes and potentiates the behavioral changes induced by the serotonin precursor, 5-hydroxytryptophan. Cardiac conduction effects of trazodone in the anesthetized dog are qualitatively dissimilar and quantitatively less pronounced than those seen with tricyclic antidepressants. Trazodone is not a monoamine oxidase inhibitor and, unlike amphetamine-type drugs, does not stimulate the central nervous system. In man, trazodone is well absorbed after oral administration without selective localization in any tissue. Since the clearance of trazodone from the body is sufficiently variable, in some patients trazodone may accumulate in the plasma.

Trazalon Absorption

Well absorbed following oral administration.

Trazalon side effects and Toxicity

LD50=96mg/kg (i.v. in mice)

Trazalon Patient Information

Trazalon Organisms Affected

Humans and other mammals