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Salural Brand names, Salural Analogs

Salural Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Salural Chemical_Formula

C15H14F3N3O4S2

Salural RX_link

No information avaliable

Salural fda sheet

Salural msds (material safety sheet)

Salural Synthesis Reference

No information avaliable

Salural Molecular Weight

421.417 g/mol

Salural Melting Point

221-223 oC

Salural H2O Solubility

108 mg/L

Salural State

Solid

Salural LogP

2.085

Salural Dosage Forms

Tablet

Salural Indication

For the treatment of high blood pressure and management of edema

Salural Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Salural Absorption

Absorbed relatively rapidly after oral administration

Salural side effects and Toxicity

No information avaliable

Salural Patient Information

No information avaliable

Salural Organisms Affected

Humans and other mammals