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Poliuron Brand names, Poliuron Analogs

Poliuron Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Poliuron Chemical_Formula

C15H14F3N3O4S2

Poliuron RX_link

No information avaliable

Poliuron fda sheet

Poliuron msds (material safety sheet)

Poliuron Synthesis Reference

No information avaliable

Poliuron Molecular Weight

421.417 g/mol

Poliuron Melting Point

221-223 oC

Poliuron H2O Solubility

108 mg/L

Poliuron State

Solid

Poliuron LogP

2.085

Poliuron Dosage Forms

Tablet

Poliuron Indication

For the treatment of high blood pressure and management of edema

Poliuron Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Poliuron Absorption

Absorbed relatively rapidly after oral administration

Poliuron side effects and Toxicity

No information avaliable

Poliuron Patient Information

No information avaliable

Poliuron Organisms Affected

Humans and other mammals