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Plusuril Brand names, Plusuril Analogs

Plusuril Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Plusuril Chemical_Formula

C15H14F3N3O4S2

Plusuril RX_link

No information avaliable

Plusuril fda sheet

Plusuril msds (material safety sheet)

Plusuril Synthesis Reference

No information avaliable

Plusuril Molecular Weight

421.417 g/mol

Plusuril Melting Point

221-223 oC

Plusuril H2O Solubility

108 mg/L

Plusuril State

Solid

Plusuril LogP

2.085

Plusuril Dosage Forms

Tablet

Plusuril Indication

For the treatment of high blood pressure and management of edema

Plusuril Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Plusuril Absorption

Absorbed relatively rapidly after oral administration

Plusuril side effects and Toxicity

No information avaliable

Plusuril Patient Information

No information avaliable

Plusuril Organisms Affected

Humans and other mammals