Intolex en es it fr

Intolex Brand names, Intolex Analogs

Intolex Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Intolex Chemical_Formula

C15H14F3N3O4S2

Intolex RX_link

No information avaliable

Intolex fda sheet

Intolex msds (material safety sheet)

Intolex Synthesis Reference

No information avaliable

Intolex Molecular Weight

421.417 g/mol

Intolex Melting Point

221-223 oC

Intolex H2O Solubility

108 mg/L

Intolex State

Solid

Intolex LogP

2.085

Intolex Dosage Forms

Tablet

Intolex Indication

For the treatment of high blood pressure and management of edema

Intolex Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Intolex Absorption

Absorbed relatively rapidly after oral administration

Intolex side effects and Toxicity

No information avaliable

Intolex Patient Information

No information avaliable

Intolex Organisms Affected

Humans and other mammals