Relan Beta
Brand names,
Relan Beta
Analogs
Relan Beta
Brand Names Mixture
- Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
- Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)
Relan Beta
Chemical_Formula
C15H14F3N3O4S2
Relan Beta
RX_link
No information avaliable
Relan Beta
fda sheet
Relan Beta
msds (material safety sheet)
Relan Beta
Synthesis Reference
No information avaliable
Relan Beta
Molecular Weight
421.417 g/mol
Relan Beta
Melting Point
221-223 oC
Relan Beta
H2O Solubility
108 mg/L
Relan Beta
State
Solid
Relan Beta
LogP
2.085
Relan Beta
Dosage Forms
Tablet
Relan Beta
Indication
For the treatment of high blood pressure and management of edema
Relan Beta
Pharmacology
Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Relan Beta
Absorption
Absorbed relatively rapidly after oral administration
Relan Beta
side effects and Toxicity
No information avaliable
Relan Beta
Patient Information
No information avaliable
Relan Beta
Organisms Affected
Humans and other mammals