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Nikion Brand names, Nikion Analogs

Nikion Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Nikion Chemical_Formula


Nikion RX_link

No information avaliable

Nikion fda sheet

Nikion msds (material safety sheet)

Nikion Synthesis Reference

No information avaliable

Nikion Molecular Weight

421.417 g/mol

Nikion Melting Point

221-223 oC

Nikion H2O Solubility

108 mg/L

Nikion State


Nikion LogP


Nikion Dosage Forms


Nikion Indication

For the treatment of high blood pressure and management of edema

Nikion Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Nikion Absorption

Absorbed relatively rapidly after oral administration

Nikion side effects and Toxicity

No information avaliable

Nikion Patient Information

No information avaliable

Nikion Organisms Affected

Humans and other mammals