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Orsile Brand names, Orsile Analogs

Orsile Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Orsile Chemical_Formula


Orsile RX_link

No information avaliable

Orsile fda sheet

Orsile msds (material safety sheet)

Orsile Synthesis Reference

No information avaliable

Orsile Molecular Weight

421.417 g/mol

Orsile Melting Point

221-223 oC

Orsile H2O Solubility

108 mg/L

Orsile State


Orsile LogP


Orsile Dosage Forms


Orsile Indication

For the treatment of high blood pressure and management of edema

Orsile Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Orsile Absorption

Absorbed relatively rapidly after oral administration

Orsile side effects and Toxicity

No information avaliable

Orsile Patient Information

No information avaliable

Orsile Organisms Affected

Humans and other mammals