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Pluryle Brand names, Pluryle Analogs

Pluryle Brand Names Mixture

  • Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
  • Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)

Pluryle Chemical_Formula


Pluryle RX_link

No information avaliable

Pluryle fda sheet

Pluryle msds (material safety sheet)

Pluryle Synthesis Reference

No information avaliable

Pluryle Molecular Weight

421.417 g/mol

Pluryle Melting Point

221-223 oC

Pluryle H2O Solubility

108 mg/L

Pluryle State


Pluryle LogP


Pluryle Dosage Forms


Pluryle Indication

For the treatment of high blood pressure and management of edema

Pluryle Pharmacology

Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.

Pluryle Absorption

Absorbed relatively rapidly after oral administration

Pluryle side effects and Toxicity

No information avaliable

Pluryle Patient Information

No information avaliable

Pluryle Organisms Affected

Humans and other mammals