Pluryle
Pluryle Brand names, Pluryle Analogs
- Aprinox
- BHFT
- Bendrofluazide
- Bendroflumethazide
- Bendroflumethiazide [Inn]
- Bendroflumethiazidum [Inn-Latin]
- Bendroflumetiazida [Inn-Spanish]
- Bendroflumetiazide [Dcit]
- Bendrofumethiazide
- Bentride
- Benuron
- Benzhydroflumethiazide
- Benzy-Rodiuran
- Benzydroflumethiazide
- Benzylhydroflumethiazide
- Benzylrodiuran
- Berkozide
- Bristuric
- Bristuron
- Centyl
- Corzide
- FT 8
- Flumersil
- Flumesil
- Intolex
- Livesan
- Naigaril
- Nateretin
- Naturetin
- Naturetin-2.5
- Naturine
- Neo-Naclex
- Neo-Rontyl
- Niagaril
- Nikion
- Orsile
- Pluryl
- Pluryle
- Plusuril
- Poliuron
- Rautrax N
- Rauzide
- Relan Beta
- Repicin
- Salural
- Salures
- Sinesalin
- Sodiuretic
- Thiazidico
- Urlea
Pluryle Brand Names Mixture
- Corzide Tab W Nadolol 40mg (Bendroflumethiazide + Nadolol)
- Corzide Tab W Nadolol 80mg (Bendroflumethiazide + Nadolol)
Pluryle Chemical_Formula
C15H14F3N3O4S2
Pluryle RX_link
No information avaliable
Pluryle fda sheet
Pluryle msds (material safety sheet)
Pluryle Synthesis Reference
No information avaliable
Pluryle Molecular Weight
421.417 g/mol
Pluryle Melting Point
221-223 oC
Pluryle H2O Solubility
108 mg/L
Pluryle State
Solid
Pluryle LogP
2.085
Pluryle Dosage Forms
Tablet
Pluryle Indication
For the treatment of high blood pressure and management of edema
Pluryle Pharmacology
Bendroflumethiazide, a thiazide diuretic, removes excess water from the body by increasing how often you urinate (pass water) and also widens the blood vessels which helps to reduce blood pressure. It inhibits Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Pluryle Absorption
Absorbed relatively rapidly after oral administration
Pluryle side effects and Toxicity
No information avaliable
Pluryle Patient Information
No information avaliable
Pluryle Organisms Affected
Humans and other mammals
