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Ifosfamide Brand names, Ifosfamide Analogs

Ifosfamide Brand Names Mixture

  • No information avaliable

Ifosfamide Chemical_Formula


Ifosfamide RX_link


Ifosfamide fda sheet


Ifosfamide msds (material safety sheet)

Ifosfamide MSDS

Ifosfamide Synthesis Reference

No information avaliable

Ifosfamide Molecular Weight

261.085 g/mol

Ifosfamide Melting Point

39-41 oC

Ifosfamide H2O Solubility

3780 mg/L

Ifosfamide State


Ifosfamide LogP


Ifosfamide Dosage Forms

Powder for constitution and administration by intravenous infusion

Ifosfamide Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Ifosfamide Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Ifosfamide Absorption

No information avaliable

Ifosfamide side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Ifosfamide Patient Information

No information avaliable

Ifosfamide Organisms Affected

Humans and other mammals