Ifosfamide/Mesna Kit en es it fr

Ifosfamide/Mesna Kit Brand names, Ifosfamide/Mesna Kit Analogs

Ifosfamide/Mesna Kit Brand Names Mixture

  • No information avaliable

Ifosfamide/Mesna Kit Chemical_Formula

C7H15Cl2N2O2P

Ifosfamide/Mesna Kit RX_link

http://www.rxlist.com/cgi/generic2/ifosfamide.htm

Ifosfamide/Mesna Kit fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=95

Ifosfamide/Mesna Kit msds (material safety sheet)

Ifosfamide/Mesna_Kit MSDS

Ifosfamide/Mesna Kit Synthesis Reference

No information avaliable

Ifosfamide/Mesna Kit Molecular Weight

261.085 g/mol

Ifosfamide/Mesna Kit Melting Point

39-41 oC

Ifosfamide/Mesna Kit H2O Solubility

3780 mg/L

Ifosfamide/Mesna Kit State

Solid

Ifosfamide/Mesna Kit LogP

-0.01

Ifosfamide/Mesna Kit Dosage Forms

Powder for constitution and administration by intravenous infusion

Ifosfamide/Mesna Kit Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Ifosfamide/Mesna Kit Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Ifosfamide/Mesna Kit Absorption

No information avaliable

Ifosfamide/Mesna Kit side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Ifosfamide/Mesna Kit Patient Information

No information avaliable

Ifosfamide/Mesna Kit Organisms Affected

Humans and other mammals