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IFEX Brand names, IFEX Analogs

IFEX Brand Names Mixture

  • No information avaliable

IFEX Chemical_Formula


IFEX RX_link


IFEX fda sheet


IFEX msds (material safety sheet)


IFEX Synthesis Reference

No information avaliable

IFEX Molecular Weight

261.085 g/mol

IFEX Melting Point

39-41 oC

IFEX H2O Solubility

3780 mg/L

IFEX State




IFEX Dosage Forms

Powder for constitution and administration by intravenous infusion

IFEX Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

IFEX Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

IFEX Absorption

No information avaliable

IFEX side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

IFEX Patient Information

No information avaliable

IFEX Organisms Affected

Humans and other mammals