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Cyfos Brand names, Cyfos Analogs

Cyfos Brand Names Mixture

  • No information avaliable

Cyfos Chemical_Formula


Cyfos RX_link

Cyfos fda sheet

Cyfos msds (material safety sheet)

Cyfos MSDS

Cyfos Synthesis Reference

No information avaliable

Cyfos Molecular Weight

261.085 g/mol

Cyfos Melting Point

39-41 oC

Cyfos H2O Solubility

3780 mg/L

Cyfos State


Cyfos LogP


Cyfos Dosage Forms

Powder for constitution and administration by intravenous infusion

Cyfos Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Cyfos Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Cyfos Absorption

No information avaliable

Cyfos side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Cyfos Patient Information

No information avaliable

Cyfos Organisms Affected

Humans and other mammals