Ifsofamide en es it fr

Ifsofamide Brand names, Ifsofamide Analogs

Ifsofamide Brand Names Mixture

  • No information avaliable

Ifsofamide Chemical_Formula


Ifsofamide RX_link


Ifsofamide fda sheet


Ifsofamide msds (material safety sheet)

Ifsofamide MSDS

Ifsofamide Synthesis Reference

No information avaliable

Ifsofamide Molecular Weight

261.085 g/mol

Ifsofamide Melting Point

39-41 oC

Ifsofamide H2O Solubility

3780 mg/L

Ifsofamide State


Ifsofamide LogP


Ifsofamide Dosage Forms

Powder for constitution and administration by intravenous infusion

Ifsofamide Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Ifsofamide Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Ifsofamide Absorption

No information avaliable

Ifsofamide side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Ifsofamide Patient Information

No information avaliable

Ifsofamide Organisms Affected

Humans and other mammals