Asta Z 4942 en es it fr

Asta Z 4942 Brand names, Asta Z 4942 Analogs

Asta Z 4942 Brand Names Mixture

  • No information avaliable

Asta Z 4942 Chemical_Formula


Asta Z 4942 RX_link

Asta Z 4942 fda sheet

Asta Z 4942 msds (material safety sheet)

Asta_Z_4942 MSDS

Asta Z 4942 Synthesis Reference

No information avaliable

Asta Z 4942 Molecular Weight

261.085 g/mol

Asta Z 4942 Melting Point

39-41 oC

Asta Z 4942 H2O Solubility

3780 mg/L

Asta Z 4942 State


Asta Z 4942 LogP


Asta Z 4942 Dosage Forms

Powder for constitution and administration by intravenous infusion

Asta Z 4942 Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Asta Z 4942 Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Asta Z 4942 Absorption

No information avaliable

Asta Z 4942 side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Asta Z 4942 Patient Information

No information avaliable

Asta Z 4942 Organisms Affected

Humans and other mammals