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Naxamide Brand names, Naxamide Analogs

Naxamide Brand Names Mixture

  • No information avaliable

Naxamide Chemical_Formula


Naxamide RX_link

Naxamide fda sheet

Naxamide msds (material safety sheet)

Naxamide MSDS

Naxamide Synthesis Reference

No information avaliable

Naxamide Molecular Weight

261.085 g/mol

Naxamide Melting Point

39-41 oC

Naxamide H2O Solubility

3780 mg/L

Naxamide State


Naxamide LogP


Naxamide Dosage Forms

Powder for constitution and administration by intravenous infusion

Naxamide Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Naxamide Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Naxamide Absorption

No information avaliable

Naxamide side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Naxamide Patient Information

No information avaliable

Naxamide Organisms Affected

Humans and other mammals