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Isofosfamide Brand names, Isofosfamide Analogs

Isofosfamide Brand Names Mixture

  • No information avaliable

Isofosfamide Chemical_Formula


Isofosfamide RX_link

Isofosfamide fda sheet

Isofosfamide msds (material safety sheet)

Isofosfamide MSDS

Isofosfamide Synthesis Reference

No information avaliable

Isofosfamide Molecular Weight

261.085 g/mol

Isofosfamide Melting Point

39-41 oC

Isofosfamide H2O Solubility

3780 mg/L

Isofosfamide State


Isofosfamide LogP


Isofosfamide Dosage Forms

Powder for constitution and administration by intravenous infusion

Isofosfamide Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Isofosfamide Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Isofosfamide Absorption

No information avaliable

Isofosfamide side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Isofosfamide Patient Information

No information avaliable

Isofosfamide Organisms Affected

Humans and other mammals